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Moreover, the
Additionally, the reduction in Dox-induced apoptosis by Ex4a-specific siRNAs was cancelled by concomitant compelled overexpression of Ex4a(+)WT1 isoform. These effects indicated that endogenous Ex4a(+)WT1 experienced a physiological functionality to promote apoptosis.DiscussionThe WT1 gene makes 4 main isoforms by option splicing of exon five (17AA) and exon 9 (KTS). All four big isoforms are over